Advancing Oncology Medicine with New Pharmaceutical Campus
U.S. Manufacturing and Clinical R&D Center | Hopewell, NJ
BeOne Medicines' (formerly BeiGene) new 400,000-sq.-ft. state-of-the-art flagship U.S. Manufacturing and Clinical R&D Center at the Princeton West Innovation Campus will help accelerate the development of innovative oncology medicines to patients around the world.
About the Facility
The campus is comprised of six separate buildings including:
- 103,000-sq.-ft. Office & Laboratory Building
- 157,000-sq.-ft. Drug Substance (DS) & Drug Processing (DP) Buildings
- 66,000-sq.-ft. Warehouse
- 48,000-sq.-ft. Central Utility Building (CUB)
- 25,000-sq.-ft. Central Utility Spine
dining area. Photo: Jeffrey Totaro, 2025
dining area. Photo: Jeffrey Totaro, 2025
ENR Mid-Atlantic Best of Regional
Project
BeOne Medicines was named ENR Mid-Atlantic's Best Manufacturing Project for 2025.
Safety By Design
With up to 450+ craft workers on-site each day, the team prioritized safety by planning work intentionally and focusing on the whole person. A cross-disciplinary safety committee fostered open communication and encouraged proactive safety planning to eliminate hazards to ensure that everyone goes home safely, every day.
Key actions included:
- Weekly safety recognition and regular site safety walks
- Monthly trade partner forums and small-group craft lunches with leadership
- Data-driven improvements, including a sitewide hand-awareness campaign and upgraded PPE requirements
- Dedicated Energy Marshall oversight for safe utility start-up and commissioning for highly technical facilities
- People-first culture-building initiatives that supported morale and well-being onsite
The Challenges
Accelerated Schedule
As the team approached the final stretch of this 27-month project, the client asked DPR to accelerate the schedule to allow for their technicians to expedite their research. With a booming life sciences construction market throughout NJ, this posed major labor resource challenges for the project.
Logistics Coordination on Campus & with Surrounding Towns
A large project on an operational campus in a bucolic town with a lot of influence required significant logistics coordination. The Princeton West Innovation Campus has numerous tenants throughout, thus limiting the amount of space available and required limiting the disruptions to other occupants. Large, oversized deliveries needed to be well coordinated logistically so as not to disturb traffic, residents, and business operations in the surrounding towns.
International Communication
Communication, collaboration and transparency are part of DPR’s recipe for successful project delivery. As an international company with stakeholders across the world, the team wanted to ensure that the customer had access to live updates and status reports throughout the project.
Supply Chain Delays
The project encountered several major supply chain delays throughout construction. The team needed to come up with creative solutions to avoid negative impacts and possible schedule slowdowns. In particular, the project required uniquely sized 6,000-amp circuit breakers to allow for potential future expansions on campus. However, the lead time was more than two years and without a solution would delay equipment start-up.
The
Challenges
Accelerated Schedule
As the team approached the final stretch of this 27-month project, the client asked DPR to accelerate the schedule to allow for their technicians to expedite their research. With a booming life sciences construction market throughout NJ, this posed major labor resource challenges for the project.
Logistics Coordination on Campus & with Surrounding Towns
A large project on an operational campus in a bucolic town with a lot of influence required significant logistics coordination. The Princeton West Innovation Campus has numerous tenants throughout, thus limiting the amount of space available and required limiting the disruptions to other occupants. Large, oversized deliveries needed to be well coordinated logistically so as not to disturb traffic, residents, and business operations in the surrounding towns.
International Communication
Communication, collaboration and transparency are part of DPR’s recipe for successful project delivery. As an international company with stakeholders across the world, the team wanted to ensure that the customer had access to live updates and status reports throughout the project.
Supply Chain Delays
The project encountered several major supply chain delays throughout construction. The team needed to come up with creative solutions to avoid negative impacts and possible schedule slowdowns. In particular, the project required uniquely sized 6,000-amp circuit breakers to allow for potential future expansions on campus. However, the lead time was more than two years and without a solution would delay equipment start-up.
The Solutions
Utilizing Self-Perform Workforce for Critical Scope Items
DPR was able to combat market impacts and limited labor availability by utilizing our self-perform work (SPW) team, thus turning over the project a month ahead of schedule. The SPW team executed the following scopes of work:
- Temporary Protection
- Doors, Frames and Hardware
- Fire Sealing Penetration
- Miscellaneous Framing
- Wall Protection
- Exterior Framing and Sheathing
This required the commitment of all local SPW carpenters, as well as an additional 30 carpenters from the Mid-Atlantic region. By utilizing SPW resources locally and regionally, the team successfully accelerated the exterior skin contract by an additional two months, keeping the building warm throughout the winter months.
Planning it Right
DPR determined that scheduling deliveries early in the morning, before peak traffic hours, would minimize their impact on surrounding towns. In collaboration with town officials, the team established an approved delivery route to the site and within the campus. When a section of I-95 collapsed along the approved route, the team acted quickly with town officials to secure a new route, ensuring critical deliveries remained on schedule. With a high volume of materials and workers on site daily, laydown areas and parking spaces filled up quickly. The team mitigated this by renting additional on-campus space, avoiding costly off-site relocation. To further streamline operations, the team identified opportunities to improve scheduling and optimize laydown space by increasing the module installation rate from three to five modules per day for the drug substance and drug project buildings.
Transparency with Technology
DPR implemented live, customized, data-driven dashboards that were accessible from anywhere in the world to track project production and progress. Additionally, project stakeholders had access to all photos and videos from regularly scheduled drone flights. This level of live transparency kept work on track, the team motivated, and held everyone accountable around the project's mission.
Strategic Sourcing
While waiting for the 6,000-amp circuit breakers, the team was able to leverage their strong relationship with the vendor, who assisted with temporarily securing used 4,000-amp circuit breakers. The team did an analysis and determined that since the larger circuit breakers were chosen to handle future expansions, the 4,000-amps were enough to start up all the current equipment, avoiding any schedule impacts to the project.
The
Solutions
Utilizing Self-Perform Workforce for Critical Scope Items
DPR was able to combat market impacts and limited labor availability by utilizing our self-perform work (SPW) team, thus turning over the project a month ahead of schedule. The SPW team executed the following scopes of work:
- Temporary Protection
- Doors, Frames and Hardware
- Fire Sealing Penetration
- Miscellaneous Framing
- Wall Protection
- Exterior Framing and Sheathing
This required the commitment of all local SPW carpenters, as well as an additional 30 carpenters from the Mid-Atlantic region. By utilizing SPW resources locally and regionally, the team successfully accelerated the exterior skin contract by an additional two months, keeping the building warm throughout the winter months.
Planning it Right
DPR determined that scheduling deliveries early in the morning, before peak traffic hours, would minimize their impact on surrounding towns. In collaboration with town officials, the team established an approved delivery route to the site and within the campus. When a section of I-95 collapsed along the approved route, the team acted quickly with town officials to secure a new route, ensuring critical deliveries remained on schedule. With a high volume of materials and workers on site daily, laydown areas and parking spaces filled up quickly. The team mitigated this by renting additional on-campus space, avoiding costly off-site relocation. To further streamline operations, the team identified opportunities to improve scheduling and optimize laydown space by increasing the module installation rate from three to five modules per day for the drug substance and drug project buildings.
Transparency with Technology
DPR implemented live, customized, data-driven dashboards that were accessible from anywhere in the world to track project production and progress. Additionally, project stakeholders had access to all photos and videos from regularly scheduled drone flights. This level of live transparency kept work on track, the team motivated, and held everyone accountable around the project's mission.
Strategic Sourcing
While waiting for the 6,000-amp circuit breakers, the team was able to leverage their strong relationship with the vendor, who assisted with temporarily securing used 4,000-amp circuit breakers. The team did an analysis and determined that since the larger circuit breakers were chosen to handle future expansions, the 4,000-amps were enough to start up all the current equipment, avoiding any schedule impacts to the project.
Notable Achievements
1.3 Million Total Work Hours
Completed on-site
Top Projects Award
NJBIZ
450+ Daily Trade Workers
On-site during the project's peak
Distinguishing Engineering Awards
NJ Alliance for Action
30 Days
Ahead of schedule
11%
Under Budget
New Jersey Biologics Manufacturing and Clinical R&D Facility Online
Early
BeiGene’s flagship U.S. biomanufacturing facility celebrates ribbon cutting ahead of schedule.
DPR Celebrates Topping Out of BeiGene’s U.S. Manufacturing & Clinical R&D
Center
A topping out celebrates the completion of the steel structures for three of the five ground-up buildings on the campus.
US Flagship Manufacturing and Clinical R&D Center Breaks Ground in New Jersey for
BeiGene
DPR Construction, IPS, and distinguished guests broke ground on BeiGene’s new Manufacturing and Clinical R&D center at the Princeton West Innovation Campus.
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