B. Braun Medical, WFI System Upgrade

BIM Project

B. Braun Medical, Inc.'s Irvine facility produces approximately 350,000 gallons per day of WFI (Water For Injection) using seven vapor compression distillation units that were manufactured & installed in the early 1970's. Although the system continues to produce acceptable water quality based on ongoing daily testing, the +35 year old stills can no longer be cost-effectively repaired and must be replaced by newer, more reliable WFI generation equipment.

In addition, Irvine facility capacity increase plans necessitate a purified water system capable of supporting higher WFI demand. The stills have far outlasted their original life expectancy of 15-20 years and must be replaced by a robust, efficient generation system that complies with current GMP design standards and satisfies future production needs.

The ultimate goal of the Irvine WFI Storage & Generation System Upgrade Project is a robust, flexible, energy-efficient, GMP compliant, cost effective, automated purified water generation system that can quickly respond to changing production needs and future capacity expansion.

Specific scope components include:

  • City feedwater booster pump replacement (3 total).
  • Three (3) pretreatment trains consisting of carbon filtration, water softening, sanitization skid, and ancillary components.
  • Three (3) 6000 gph vapor compression stills.
  • Two (2) Storage Tanks (15k gallons each).
  • Interconnecting piping, pumps, heat exchangers.
  • All necessary instrumentation and controls for a fully automated system.
  • Arch/infrastructure/support utility modifications.
  • Relocation of existing maintenance support areas and Mens bathroom.
  • All required installation, commissioning & qualification activities/costs/permits/fees.
  • Upgrade of existing Reverse Osmosis system to ensure reliable sterilizer process supply.
  • The new generation & storage system will be interfaced with the existing WFI distribution system – no modifications or enhancements to the current piping system are included in this scope.
  • Existing brine pits will be reused.

BIM Features

  • Proposal
  • Self Perform Work Detailing
  • Self Perform Work Tracking
  • MEP Coordination
  • 4D Sequencing
  • Constructability Analysis
  • Laser Scanning
  • Site Logistics Planning

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